Members of the Bush family seemed uneager to discuss her entry into the marriage debate.

Bush's Daughter Backs Gay Marriage - NYTimes.com:

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“No matter what party they belong to, young Americans believe in basic fairness and equality,” said Brian Ellner.

Meghan McCain, the daughter of John McCain, the 2008 Republican presidential nominee, has become an outspoken supporter of same-sex marriage, despite her father’s opposition to it. And Mary Cheney, the lesbian daughter of Vice President Dick Cheney, has forcefully backed it as well — and is widely credited with helping to persuade her father to do the same.

In the case of Mr. McCain, Mr. Cheney and Mr. Bush, it is not just their children who have supported it. So, to varying degrees, have their wives. Laura Bush, in a television interview in May, said, “When couples are committed to each other and love each other” they should have “the same sort of rights that everyone has.”

Ms. McCain, a blogger and author, has said it is unhealthy for members of political families to paper over disagreements on issues of social justice merely to project an image of harmony. “Wives and children should be able to speak their piece,” she said in a television interview last year. “I think it shows healthy dynamics within a family. We shouldn’t all think one way, and think one thing.”

Barbara Bush, who started a nonprofit group focused on global health, rarely speaks out on American political issues, making her foray into the same-sex marriage debate so striking. But for years, those close to her say, she has surrounded herself with gay friends — at Yale, where she was an undergraduate, and in New York City, where she worked in the design world.

C. Brian Smith, a friend from college who is gay, recalled that the Yale Ms. Bush inhabited was filled with openly gay students and unbothered by questions about sexuality. “She had that mind-set,” he said. “She was loved by the gay community at Yale.”

Members of the Bush family seemed uneager to discuss her entry into the marriage debate. Ms. Bush declined an interview request. A spokesman for Mr. Bush said he had no comment. Her sister, Jenna Bush Hager, a correspondent for “Today,” has not publicly discussed the topic.